Folate Cycle is the cycle in which folic acid-a manmade supplement-and folate are processed and converted into their active form methylfolate. Methylfolate is needed to break down the amino acid homocysteine. In large quantities, this amino acid can cause damage to the lining of your arteries.
The MTHFR enzyme is needed for methylation, a metabolic process that repairs DNA, switches genes on and off, and numerous other important functions. When there is a mutation, the enzyme's ability to assist in methylation can be dramatically reduced. Methylation impacts many of the body’s biochemical reactions. Methylation regulates the cardiovascular, neurological, reproductive, and detoxification systems.
The MTHFR enzyme is needed for methylation, a metabolic process that repairs DNA, switches genes on and off, and numerous other important functions. When there is a mutation, the enzyme's ability to assist in methylation can be dramatically reduced. Methylation impacts many of the body’s biochemical reactions. Methylation regulates the cardiovascular, neurological, reproductive, and detoxification systems.
The MTHFR mutation decreases the body's ability to regulate the production of an important antioxidant, glutathione. Glutathione plays an imperative role in detoxification of disease toxins in the body. When there are low levels of glutathione in the body, the disease process is heightened, resulting in a build up of toxins. This can lead to autism, ADHD, autoimmune diseases, multiple sclerosis, fibromyalgia, miscarriages, addiction, and heart disease.